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Metabolix to Conduct a Webcast of Its Fourth Quarter 2007 Earnings Call

Partnership with St. Louis-based Danforth Plant Science Center Receives Funding from the Missouri Life Sciences Research Board

March 3, 2008

Metabolix, Inc. (NASDAQ: MBLX) a bioscience company focused on developing clean, sustainable solutions for plastics, chemicals and energy, announced today that it will be releasing its fourth quarter 2007 financial results after the market close on Tuesday, March 11, 2008. The full text of the release will also be available on the Company’s website at www.metabolix.com.

Jay Kouba, the Company’s Chairman of the Board and CEO will host a conference call on the same day at 4:30 p.m. (Eastern). The conference call will be webcast and can be accessed from the Company’s website at www.metabolix.com in the investor relations section.

To listen to a telephonic replay of the conference call, dial toll-free 1-888-203-1112 or 1-719-457-0820 for international callers and enter passcode 4377791. The replay will be available beginning at 7:30 p.m. (Eastern) on Tuesday, March 11, 2008 and will last through 11:59 PM (Eastern) March 18, 2008. In addition, the webcast will be archived on the Company’s website in the investor relations section.

About Metabolix
Founded in 1992, Metabolix, Inc. is an innovation driven bioscience company focused on providing sustainable solutions for the world’s needs for plastics, chemicals and energy. The Company is taking a systems approach, from gene to end product, integrating sophisticated biotechnology with advanced industrial practice. Metabolix is now developing and commercializing Mirel™ bioplastics, a sustainable and biodegradable alternative to petroleum-based plastics. Mirel is suitable for injection molding, extrusion coating, cast film and sheet, blown film and thermoforming. Metabolix is also developing a proprietary platform technology for co-producing plastics, chemicals and energy, from crops such as switchgrass, oilseeds and sugarcane.

Metabolix and Archer Daniels Midland Company (ADM) are commercializing Mirel through a joint venture called Telles. The first commercial scale Mirel production plant is being constructed adjacent to ADM's wet corn mill in Clinton, Iowa. The plant is expected to begin operations in late 2008 and is designed to produce up to 110 million pounds of Mirel annually. Mirel will reduce reliance on petroleum and decrease environmental impacts relative to conventional petroleum-based plastics.

For more information, please visit www.metabolix.com. (MBLX-E)

View Full Press Release (PDF)

Contacts:

Investors:
Kathleen Heaney
Integrated Corporate Relations
(203) 803-3585
kheaney@icrinc.com