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Metabolix Announces CFO to Resign and Assume Other Duties

July 30, 2007

Cambridge, Massachusetts. Metabolix, Inc. (NASDAQ: MBLX) a company developing and commercializing environmentally sustainable and biodegradable plastic, announced today that Thomas G. Auchincloss, Jr. will be resigning from his positions as Chief Financial Officer, Vice President, Finance and Corporate Development and Treasurer of the company effective August 10, 2007. Mr. Auchincloss will continue to be employed by Metabolix and will work to progress ongoing business development projects, to assist with transition and to handle other matters. A search for a successor has been initiated.

About Metabolix
Founded in 1992, Metabolix, Inc. is an innovation driven bioscience company providing clean, sustainable solutions for the world’s needs for plastics, fuels, and chemicals. The Company is taking a systems approach, from gene to end product, integrating sophisticated biotechnology with advanced industrial practice. Metabolix is now developing and commercializing Mirel™ biobased plastics as the sustainable and biodegradable alternative to petroleum-based plastics. Metabolix is also developing a proprietary platform technology for co-producing biobased plastics, biofuels and chemical products in biomass energy crops such as switchgrass. For more information, please visit www.metabolix.com. (MBLX-G)

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