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Publications
Authored by Metabolix Research Staff

2007

Chemically inducible expression of the PHB biosynthetic pathway in Arabidopsis

Lauralynn Kourtz, Kevin Dillon, Sean Daughtry, Oliver P. Peoples  and Kristi D. Snell

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2005

Kristi Snell, Ph.D., Presentation at the 27th Symposium on Biotechnology for Fuels and Chemicals, Denver, Colorado May 2, 2005.

"A Novel Thiolase-Reductase Gene Fusion Promotes the Production of Polyhydroxybutyrate in Arabidopsis." Lauralynn Kourtz, Kevin Dillon, Sean Daughtry, Lara L. Madison1, Oliver Peoples, and Kristi D. Snell, Plant Biotechnology Journal, 2005.

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2004

Bohmert, K., Peoples, O. P., Snell, K. D. “Metabolic Engineering: Plastids as Bioreactors.” In Molecular Biology and Biotechnology of Plant Organelles. H. Daniell and C. D. Chase. Netherlands, Kluwer Academic Publishers: 559-585. 2004.

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2002

“YfcX Enables Medium-Chain-Length Poly(3-Hydroxyalkanoate) Formation from Fatty Acids in Recombinant Escherichia coli fadB Strains.” Snell, K. D., Feng, F., Zhong, L., Martin, D., Madison, L. J. Bacteriol., 2002, 184, 5696-5705.

"Bioplastics". Skraly, F. In Encyclopedia of Environmental Microbiology. J. Wiley & Sons, 2002.

"Polyhydroxyalkanoate Polymers and Their Production in Transgenic Plants". Snell, K.D. and Peoples, O. P. Metabolic Engineering, 4, 29-40, 2002.

"Polymers Biosynthesized by Microorganisms: Polyhydroxyalkanoates". Martin, D.P., Williams, S.F. and Skraly, F.A. In Methods of Tissue Engineering. Chapter 48. Academic Press, 2002.

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1999

"Mirel applications: addressing the price performance issue". Williams, S.F., Martin, D.P., Horowitz, D.M. and Peoples, O.P. I: Tissue Engineering. Int. J. Biol. Macromol. 25: 111-12, 1999.

Novel thermal route to an amorphous, film-forming polymer latex. Daniel M. Horowitz et al. Macromolecules 1999, 32, 3347-3352.

Reduction of cell lysate viscosity during processing of poly(3-hydroxyalkanoates) by chromosomal integration of the staphylococcal nuclease gene in Pseudomonas putida. Zhuang L. Boynton et al. Appl. Environ. Microbiol. 1999, 65, 1524-1529.

Metabolic engineering of poly(3-hydroxyalkanoates): from DNA to plastic. Lara L. Madison and Gjalt W. Huisman. Microbiol. Mol. Biol. Rev. 1999, 63, 21-53.

Extracellular polymerization of 3-hydroxyalkanoate monomers by the synthase from Alcaligenes eutrophus. David P. Martin et al. In Biochemical Principles and Mechanisms of Biosynthesis and Biodegradation of Polymers; Wiley-VCH: Weinheim, 1999; pp 168-175.

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1997

Making plastics green. Simon F. Williams and Oliver P. Peoples. Chem. Br. 1997, 33(12), 29-32.

Aspects of PHB granule formation in vitro. David P. Martin and Tillman U. Gerngross. In 1996 International Symposium on Bacterial Polyhydroxyalkanoates; NRC Research Press: Ottawa, 1997; pp 28-35.

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1996

Biodegradable plastics from plants. Simon F. Williams and Oliver P. Peoples. CHEMTECH 1996(9), 38-44.

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1995

Enzyme-catalyzed synthesis of poly[(R)-(-)-3-hydroxybutyrate]: formation of macroscopic granules in vitro . Tillman U. Gerngross and David P. Martin. Proc. Natl. Acad. Sci. USA 1995, 92, 6279-6283.

Biomimetic, amorphous granules of polyhydroxyalkanoates: composition, mobility, and stabilization in vitro by proteins. Daniel M. Horowitz et al. Can. J. Microbiol. 1995, 41, 115-123.

Metabolic engineering and applications of polyhydroxyalkanoates (Mirels). Simon F. Williams et al. In Proceedings of the Second Biomass Conference of the Americas: Energy, Environment, Agriculture, and Industry; 1995; pp 1130-1140.

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1994

Overexpression and purification of the soluble polyhydroxyalkanoate synthase from Alcaligenes eutrophus: evidence for a required post-translational modification for catalytic activity. Tillman U. Gerngross et al. Biochemistry 1994, 33, 9311-9320.

Phase separation within artificial granules from a blend of polyhydroxybutyrate and polyhydroxyoctanoate: biological implications. Daniel M. Horowitz et al. Polymer 1994, 34, 5079-5083.

Amorphous, biomimetic granules of polyhydroxybutyrate: preparation, characterization, and biological implications. Daniel M. Horowitz et al. J. Am. Chem. Soc. 1994, 116, 2695-2702.

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1993

Amorphous polymer granules. Daniel M. Horowitz et al. Nature 1993, 363, 23.

Immunocytochemical analysis of poly-3-hydroxybutyrate (PHB) synthase in Alcaligenes eutrophus H16: localization of the synthase enzyme at the surface of PHB granules. Tillman U. Gerngross et al. J. Bacteriol. 1993, 175, 5289-5293.

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1992

Biosynthetic thiolase from Zoogloea ramigera: mutagenesis of the putative active-site base Cys-378 to Ser-378 changes the partitioning of the acetyl-S-enzyme intermediate. Simon F. Williams et al. J. Biol. Chem. 1992, 267, 16041-16043.

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1990

Polyhydroxybutyrate (PHB): A model system for biopolymer engineering: II. Oliver P. Peoples et al. In Novel Biodegradable Microbial Polymers; Kluyer Academic Publishers: Dordrecht, 1990; pp 191-202.

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1989

Fine structural analysis of the Zoogloea ramigera phbA-phbB locus encoding 3-ketothiolase and acetoacetyl-CoA reductase: nucleotide sequence of phbB. Oliver P. Peoples et al. Mol. Microbiol. 1989, 3, 349-357.

Poly-3-hydroxybutyrate (PHB) biosynthesis in Alcaligenes eutrophus H16. Identification and characterization of the PHB polymerase gene (phbC). Oliver P. Peoples et al. J. Biol. Chem. 1989, 264, 15298-15303.

Poly-3-hydroxybutyrate biosynthesis in Alcaligenes eutrophus H16. Characterization of the genes encoding ketothiolase and acetoacetyl-CoA reductase. Oliver P. Peoples et al. J. Biol. Chem. 1989, 264, 15293-15297.

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1987

Polyhydroxybutyrate (PHB): a model system for biopolymer engineering. Oliver P. Peoples et al. Prog. Biotechnol. 1987, 3, 51-56.

Biosynthetic thiolase from Zoogloea ramigera. III. Isolation and characterization of the structural gene. Oliver P. Peoples et al. J. Biol. Chem. 1987, 262, 97-102.

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